Goslin 2.0

The next version of GOSLIN is there, supporting the updated lipid nomenclature and new lipid classes! Goslin is the first grammar-based computational library for the recognition/parsing and normalization of lipid names following the hierarchical lipid shorthand nomenclature. The new version Goslin 2.0 implements the latest nomenclature and adds an additional grammar to recognize systematic IUPAC-IUB fatty acyl names as stored, e.g., in the LIPID MAPS database and is perfectly suited to update lipid names in LIPID MAPS or HMDB databases to the latest nomenclature. Goslin 2.0 is available as a standalone web application with a REST API as well as C++, C#, Java, Python 3, and R libraries. Importantly, it can be easily included in lipidomics tools and scripts providing direct access to translation functions. All implementations are open source. https://pubs.acs.org/doi/10.1021/acs.analchem.1c05430

HFSPO (Human Frontier Science Program)

With great pleasure, I announce that we were awarded through the Human Frontier Science Program (HFSPO). We are eager to start the chapter on synaptoneurolipidomics, and we are thrilled to start this great project with labs around the globe:

Michael Kreutz: kreutzlab.com

Steven Verhelst: verhelstlab.net

Shane Ellis: ihmri.org.au/researchers/dr-shane-ellis

Robert Ahrends:lipidomics.at

We Love Lipids

We are delighted to contribute to the "We Love Lipids" Tutorial in 2022, introducing lipidomics and lipid sciences. Please save the dates and meet us again soon!

https://lipidomicssociety.org/2022/02/10/ils-tutorials-2022/

Neurolipidomics

Finally, it is done after several years of hard work; our first synaptoneurolipidomics manuscript has been published! We are very grateful to the LIFS-team for their support!

How an enriched environment fires up our synapses

Postgenomic research reveals the role of peptides and lipids in the context of signal transduction.

The processing of sensory impressions and information depends very much on how the synapses in our brain work. Our team and neuroscientist Michael R. Kreutz from Leibniz Institute for Neurobiology in Magdeburg showed how lipid and protein regulation impact the brain’s processing in a beautiful and stimulating environment. The lipids located in the membranes of the synapses are central to signal transmission, and the researchers report in “Cell Reports” the synaptic impact of specific lipids. https://doi.org/10.1016/j.celrep.2021.109797