Title Global analysis of putative phospholipases in Plasmodium
falciparum reveals an essential role of the phosphoinositide-
specific phospholipase C in parasite maturation
Contacts

Paul-Christian Burda, This email address is being protected from spambots. You need JavaScript enabled to view it.
Centre for Structural Systems Biology, Hamburg, Germany
Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
University of Hamburg, Hamburg, Germany

Michael J. Blackman, This email address is being protected from spambots. You need JavaScript enabled to view it.
Malaria Biochemistry Laboratory, The Francis Crick Institute, London, United Kingdom
Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical
Medicine, London, United Kingdom

Tim-Wolf Gilberger, This email address is being protected from spambots. You need JavaScript enabled to view it.
Centre for Structural Systems Biology, Hamburg, Germany
Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
University of Hamburg, Hamburg, Germany

Publication

Peer reviewed publication: DOI: 10.1128/mbio.01413-23, Parasitology, ASFM, July, 2023

Preprint: DOI: 10.1101/2021.06.28.450158, BioRxive, CSHL, June 24th, 2021

Accession LCE00000008
Status In curation
Organism Plasmodium falsiparium (NCBITaxon:5833), Knockout (NCIT:C22491): PF3D7_1476800, PI-PLC
Supplementary Material

Manuscript Supplements:

  • Supplementary File 1 - Oligonucleotides and other synthetic DNA used in this study: Supplemental File 1.xlsx
  • Supplementary File 2 - Lipid abundances (relative abundances mol% and pmol/million cells) and paired t-test analysis, source data for Figures 4C,D and S7: Supplemental File 2.xlsx
  • Supplementary File 3 - Lipid standards used for quantification, LC Gradient and ESI source conditions: Supplemental File 3.xlsx

Lipidomics Results:

Created July 7th, 2021
Last Updated July 4th, 2023
Curators Nils Hoffmann

 


Uni Wien
l.mpi
fz borstel
Forschungszentrum Jülich

 
Supported by the German BMBF
Supported by the Austrian BMBWF