Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards

Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards

Abstract

In this community effort, we compare measurements between 34 laboratories from 19 countries, utilizing mixtures of labelled authentic synthetic standards, to quantify by mass spectrometry four clinically used ceramide species in the NIST (National Institute of Standards and Technology) human blood plasma Standard Reference Material (SRM) 1950, as well as a set of candidate plasma reference materials (RM 8231). 

Torta, F. T., Hoffmann, N., Burla, B. et al., Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards, Nature Communications (2024)

doi: 10.1038/s41467-024-52087-x