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Quick Start

Click on the link above for a quick overview and start to LipidXplorer

News

2019-02-12 LipidXplorer available as LIFS Web Application

A web-based version of LipidXplorer is available via the LIFS web application portal. Please note that the application is not yet publicly available. If you want to test it, please request access.

2018-03-01 LipidXplorer Wiki now hosted by LIFS

As of March 1st, 2018, the LipidXplorer Wiki has been relocated to the LIFS infrastructure.

2016-05-09 New release: LipidXplorer Version 1.2.7

The new version Single file installer LipidXplorer v1.2.7 source code can now be downloaded. It includes some minor bug fixes and some speed improvements for MFQL lipid identification.

LXMerge: A tool for merging multiple results

Get LipidXplorer

If you are on Windows you can try the Single file installer for Windows

LipidXplorer is published under GPL and available here: [LipidXplorer on Sourceforge]. Check out the LipidXplorer installation instructions for help.

Feature suggestions

LipidXplorer will be further developed all the time. If you have suggestions for useful features, please write to the LipidXplorer mailing list and we will post them here. We also will post a status report on the suggested features: the LipidXplorer wishlist.

LipidXplorer MFQL Bibliography

Yadav S, Garner K, Georgiev P, Li M, Gomez-Espinosa E, Panda A, Mathre S, Okkenhaug H, Cockcroft S and Raghu P: RDGBα, a PI-PA transfer protein regulates G-protein coupled PtdIns(4,5)P2 signalling during Drosophila phototransduction JCS 2015 July

Khaliullina H, Bilgin M, Sampaio JL, Shevchenko A, Eaton S:Endocannabinoids are conserved inhibitors of the Hedgehog pathway PNAS 2015 Feb 2

Hebbar S, Schulz W D, Sauer U and Schwudke D :Laser Capture Microdissection Coupled with On-Column Extraction LC-MSn Enables Lipidomics of Fluorescently Labeled Drosophila Neurons Anal. Chem. 2014 May 12, 86(11)

Papan C, Penkov S, Herzog R, Thiele C, Kurzchalia T, Shevchenko A:Systematic screening for novel lipids by shotgun lipidomics. Anal. Chem. 2014 Jan 28, 86(5)

Gaessler J, Bornstein T D, Goel D, Bhalla V P, Lohmann T, Wolf T, Koch M, Qin Y, Licinio J, Wong M-L, Chavakis T, Xu A, Shevchenko A, Schuhmann K, Schwarz P E H, Patel A, Bornstein S R:Lipidomic profiling before and after Roux-en-Y gastric bypass in obese patients with diabetes The Pharmacogenomics Journal 2013 Dec 24

Herzog R, Schwudke D, Shevchenko A:LipidXplorer: Software for Quantitative Shotgun Lipidomics Compatible with Multiple Mass Spectrometry Platforms Current Protocols in Bioinformatics 2013 Oct 15

Contact

For any questions and suggestions please put them on the [LipidXplorer Google Group]

If you do not want to join google, please write us (mirandaa@mpi-cbg.de or herzog@mpi-cbg.de) an email and I'll add you to the group.

If you want to contribute to the Wiki please write to mirandaa@mpi-cbg.de or herzog@mpi-cbg.de or also to the google group.

Known bugs

Please check out the [LipidXplorer Google Group] to be up-to-date on found bugs.

Bug reports

Please send Bug reports directly to mirandaa@mpi-cbg.de

Example spectra

Example spectra for the LipidXplorer tutorial

Spectra of E.coli acquired on the LTQ Orbitrap with different resolution settings:File:Spectra tutorial.zip

All spectra used in the LipidXplorer article

Spectra of E.coli and bovine heart acquired on LTQ Orbitrap XL, LTQ Orbitrap Velos and ABI QStar pulsar (in DDA and MPIS mode):File:Spectra article.zip