LipidCompass

Eva Herker, This email address is being protected from spambots. You need JavaScript enabled to view it.
Institute of Virology, Philipps-University Marburg, Marburg, Germany

Dominik Schwudke, This email address is being protected from spambots. You need JavaScript enabled to view it.
Division of Bioanalytical Chemistry, Research Center Borstel - Leibniz Lung Center, Borstel, Germany
German Center for Infection Research, Thematic Translational Unit Tuberculosis, Partner Site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany
German Center for Lung Research (DZL), Airway Research Center North (ARCN), Research Center Borstel - Leibniz Lung Center, Borstel, Germany

Peer reviewed publication: 

Hehner, J., Schneider, L., Woitalla, A. et al. Glycerophospholipid remodeling is critical for orthoflavivirus infection. Nat Commun 15, 8683 (2024).
https://www.nature.com/articles/s41467-024-52979-y
Published: 07 October 2024

Preprint: not available

LCE00000015 (LipidCompass)

MTBLS11030: Glycerophospholipid remodeling is critical for orthoflavivirus infection (MetaboLights)

Manuscript Supplements:

• Supplementary Table S1 - Lipid quantities after viral infection at different timepoints (322 lipids, 16 classes): 240123_Table_S1.xlsx
• Supplementary Table S2 - FA composition of membrane and storage lipids species changes following
  infection for PC, PE, PS, and TAG: 240123_Table_S2.xlsx
• Lipidomics Reporting Checklist: Lipidomics Reporting Checklist PDF

Lipidomics Results:

• LipidXplorer Positive ion mode analysis settings: 211129_Virus_Eva_Herker-project.lxp
• LipidXplorer Positive ion mode report (w/ MFQL): 211129_Virus_Eva_Herker_pos-report_screen.html
• LipidXplorer Positive ion mode analysis (TAG FA Content) settings: 220719_TAG_FAs.lxp
• LipidXplorer Positive ion mode report (TAG FA Content, w/ MFQL): 211129_Virus_Eva_Herker_pos-report.html
• LipidXplorer Negative ion mode analysis settings: 211129_Virus_Eva_Herker-project_neg.lxp
• Cholesterol determination after acetylation positive ion mode report (w/ MFQL): 210820_Virus_EH_Batch1_Batch2_Batch3_Chol-report.html
• Cholesterol determination after acetylation negative ion mode report (w/ MFQL): 211022_Virus_EH_Batch1_Batch2_Batch3_neg-report.html

Paul-Christian Burda, This email address is being protected from spambots. You need JavaScript enabled to view it.
Centre for Structural Systems Biology, Hamburg, Germany
Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
University of Hamburg, Hamburg, Germany

Michael J. Blackman, This email address is being protected from spambots. You need JavaScript enabled to view it.
Malaria Biochemistry Laboratory, The Francis Crick Institute, London, United Kingdom
Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical
Medicine, London, United Kingdom

Tim-Wolf Gilberger, This email address is being protected from spambots. You need JavaScript enabled to view it.
Centre for Structural Systems Biology, Hamburg, Germany
Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
University of Hamburg, Hamburg, Germany

Peer reviewed publication: DOI: 10.1128/mbio.01413-23, Parasitology, ASFM, July, 2023

Preprint: DOI: 10.1101/2021.06.28.450158, BioRxive, CSHL, June 24th, 2021

Manuscript Supplements:

• Supplementary File 1 - Oligonucleotides and other synthetic DNA used in this study: Supplemental File 1.xlsx
• Supplementary File 2 - Lipid abundances (relative abundances mol% and pmol/million cells) and paired t-test analysis, source data for Figures 4C,D and S7: Supplemental File 2.xlsx
• Supplementary File 3 - Lipid standards used for quantification, LC Gradient and ESI source conditions: Supplemental File 3.xlsx

Lipidomics Results:

• LipidXplorer Negative Ion Mode report: mzml_neg-report.html
• LipidXplorer Positive Ion Mode report: mzml_pos-report.html
• lxPostman Quantified and Processed LipidXplorer Results report: 221014_184847_lxPostman_report_Burda.xlsx